I keep thinking it may be COPD or chronic bronchitis...I even compared the cough to AIDS...but knew I test neg for AIDS. So if I stay on anti-biotics but never get past my respiratory problems, does it sound like Primary Immunodeficiency? I just saw a commercial on Headline News. I had never heard of Primary Immunodeficiency before. It does seem to explain what I have been dealing with. Anyone here have any experience with Primary Immunodeficiency or its patients? I have been bronchil my whole life. Right now I have atelectasis or partially collapsed lung. I have been to the doctor twice in ten days. I am going to ask for t cell and b cell count next time I go...January... yes with a collapsed lung...you are definately short of breath...that is how I found out about the collapsed lung...I went in especially beacuse of the short of breath thing. There has to be a BIG reason why I never heal, meds do me no good, and I seem to be constantly sick. I think is PI or CVI. I was around my granddaddy who smoke for years. He eventually died of asbestos cancer which worries me. I could have breathed those fibers from his clothing. He mixed paint for making ceiling board. He worked for Owens Corning.